Dr Mat Clement, a Research Fellow funded by the WCRC, has been awarded a Future Leaders Fellowship by the Brain Tumour Charity, showing the potential in his research project ‘Manipulating T-cell immune responses in order to improve anti-Glioblastoma immunity.’
Glioblastoma (GBM), an aggressive and currently incurable form of brain cancer, presents a daunting challenge. Current treatment options, including surgery, chemotherapy, and radiotherapy, often prove insufficient, with tumours recurring despite intervention. In this context, Dr Clement’s research is aiming to revolutionise treatment through harnessing the power of the immune system. His research focuses on understanding and manipulating T-cell responses, pivotal players in the body’s immune defence system, to enhance their anti-tumour capabilities.
Drawing from his extensive background in studying immune responses to chronic viral infections and neurodegeneration, Dr Clement brings a wealth of knowledge and expertise to this research project. His interdisciplinary approach aims to unlock new insights into the mechanisms underlying GBM progression and pave the way for novel therapeutic interventions.
Expressing his gratitude for the support received from the WCRC, Dr Clement remarked, “I’m absolutely over the moon to receive this Fellowship, I couldn’t have done it without the WCRC supporting me and investing in me, the Centre has made a massive difference to my career and for that I am very grateful.”
Prof Awen Gallimore, Dr Clement’s mentor, Co-Director of the Systems Immunity University Research Institute (SIURI) and Immuno-oncology theme lead for CReSt said: “Mat is uniquely placed to capitalise on his research experience in studying the role of T-cells in Glioblastoma and will position himself between world-leading brain cancer researchers, immunologists and neuroscientists within Cardiff University. He is distinguished by his cross-disciplinary and collaborative approach and widely recognised as one of our future stars. His project is a highly novel area, built on his previous work in viral infection and Alzheimers disease. It is exciting that he is able to bring these insights into brain cancer research.”
Prof Mererid Evans, Director at the WCRC said: “Dr Mat Clement’s achievement is a source of immense pride for the WCRC. We are absolutely delighted, and the entire team joins me in congratulating him. A Future Leaders Fellowship, such as this, epitomises the aspirations we hold for our funded researchers. Mat’s success serves as a shining example of the calibre of talent we aim to nurture and support across Wales. We look forward to continuing our mission of empowering more exceptional researchers like Mat in the future”